Session 1

08:20 - 08:30
 

Welcome from the committee
 

08:30 - 09:20
 

Highlight Speaker: Ruth Nussinov, National Cancer Institute (USA)
Mapping SNPs and oncogenic mutations onto structural pathways of cancer and inflammation.

09:20 - 09:45
 

Christopher Yates and Michael Sternberg.
Disease-Propensity and nsSNP Phenotype Prediction.

09:45 - 10:10
 
 
 

Lukas Folkman, Bela Stantic and Abdul Sattar.
Improving mutation-induced stability changes prediction in unseen non-homologous proteins with feature-based multiple models.
 

10:10 - 10:30
 

Coffee Break
 

10:30 - 10:55
 

Martin Kircher, Daniela Witten, Gregory Cooper and Jay Shendure.
A general framework for estimating the relative pathogenicity of human genetic variants.

10:55 - 11:20
 

Bjoern Stade, David Ellinghaus, Britt-Sabina Petersen and Andre Franke.
snpActs: A versatile analysis tool for annotating and prioritizing SNV data sets.

11:20 - 12:10
 

Keynote Presentation: Manolis Kellis, MIT (USA).
Regulatory Genomics and Epigenomics of complex disease.

12:10 - 12:25

Company Presentation Frank Schacherer, BIOBASE GmbH.

12:25 - 13:05

Lunch Break and Poster Session with the Authors

Session 2

13:15 - 14:05
 

Highlight Presentation: Paul Flicek, EMBL-EBI (UK)
Using comparative genomics to restrict the search space of regulatory variants causing rare disease.

14:10 - 14:35
 

Graham Ritchie, Paul Flicek and Eleftheria Zeggini.
Functional annotation of non-coding variants.

14:35 - 15:00
 

Ammar Naqvi, Tiange Cui and Andrey Grigoriev.
Visualization of nucleotide substitutions in the transcriptome.

15:00 - 15:25
 
 

Lipika Pal, Chen Cao, Chen-Hsin Yu and John Moult.
GWAS and Drug Targets.
 

15:25 - 15:45
 

Coffee Break
 

15:45 - 16:35
 
 

Keynote Presentation: Alon Keinan, Cornell University (USA).
Recent human population growth: rare variants, mutation load, and complex disease.
 

16:35 - 17:15 
 

CAGI corner: Steven Brenner, University of California Berkeley (USA).
 

17:15 - 18:05
 
 

Round Table discussion:
Sean Mooney Buck Institute, Novato (CA)
 

18:05 - 18:15

Closing remarks from the committee.